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en-wikipedia-org-6449		Agriculture in the United States - Wikipedia			.html	text/html	6531	838	65	Although agricultural activity occurs in every state in the union, it is particularly concentrated in the Great Plains, a vast expanse of flat, arable land in the center of the nation in the region west of the Great Lakes and east of the Rocky Mountains. Main article: History of agriculture in the United States In the early colonial south, raising tobacco and cotton was common, especially through the use of slave labor until the Civil War. In the northeast, slaves were used in agriculture until the early 19th century.[citation needed] In the Midwest, slavery was prohibited by the Freedom Ordinance of 1787. United States agriculture production in 2018[edit] Most of these groups are funded by the National Institute for Occupational Safety and Health, the US Department of Agriculture, or other state agencies.[43] Centers include: High Plains Intermountain Center for Agricultural Health and Safety, Colorado State University, Fort Collins, CO[46]	./cache/en-wikipedia-org-6449.html	./txt/en-wikipedia-org-6449.txt