id author title date pages extension mime words sentences flesch summary cache txt work_3qyany4qanex7htarbeii7itki Geoffrey A. Walford Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci 2016.0 12 .pdf application/pdf 11770 3388 75 Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci approach to discover new common genetic variants associated with insulin sensitivity is to perform GWAS using a removing lower-frequency SNPs in model 3, a sensitivity analysis was performed using the MAC ,20 filter on a cohortwise basis in both the discovery and replication cohorts. approach in model 3 (10), and with direct measures of insulin sensitivity were included in these analyses (7). To analyze the association with fasting insulin and ISI in a comparable sample, we also examined the subset of discovery cohorts that excluded given its high heterogeneity) with fasting insulin and ISI in a subset of the discovery cohort. sensitivity signal rs2943641 (IRS1) (10), and the association with the ISI in model 2 was greatly reduced by conditioning rs13422522 on rs2943641 in the discovery cohort ./cache/work_3qyany4qanex7htarbeii7itki.pdf ./txt/work_3qyany4qanex7htarbeii7itki.txt