id author title date pages extension mime words sentences flesch summary cache txt work_4qtjvy3idnc4df56lz7ur6nega Rebecca J. Sardell Heritability of Choroidal Thickness in the Amish 2016.0 8 .pdf application/pdf 6319 1129 51 was used to classify eyes into categories using a modified Clinical Age-Related Maculopathy Staging (CARMS) Repeatability and heritability of choroidal thickness and its phenotypic and genetic correlations with the AMD phenotype (CARMS category) were estimated using a generalized linear mixed model (GLMM) approach Main Outcome Measures: Heritability of choroidal thickness and its phenotypic and genetic correlation with Results: Phenotypic correlation between choroidal thickness and CARMS category was moderate (Spearman's rank correlation, rs ¼ �0.24; n ¼ 1313 eyes) and significant (GLMM posterior mean, �4.27; 95% credible However, because the genetic correlation between choroidal thickness and AMD severity To assess the use of choroidal thickness as an AMD endophenotype we quantified (1) its overall phenotypic correlation with the Scatterplots showing the phenotypic correlation of (A) Clinical Age-Related Maculopathy Staging (CARMS) category and (B) subfoveal Phenotypic but not genetic correlation between choroidal thickness and AMD has been ./cache/work_4qtjvy3idnc4df56lz7ur6nega.pdf ./txt/work_4qtjvy3idnc4df56lz7ur6nega.txt