id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_5qjmgtplsfgdlgfs6d53glkdw4	S Bundey	Low segregation ratios in autosomal recessive disorders	1993.0	3	.pdf	application/pdf	2274	380	69	Low segregation ratios in autosomal recessive account of a reduced segregation ratio in cartilage-hair hypoplasia (CHH) in Finland' and of often been found in genetic studies of supposedly recessive diseases, such as those on chronic spinal muscular atrophy,3 osteogenesis unexpectedly low proportions of affected sibs may have many causes which can be considered under the headings of parental behaviour, observer error, and biological factors. Secondly, parents may not report earlier affected sibs, perhaps because of fear of stigmatisation, or families with an affected child contained an Most interesting of all are the possible biological explanations for a low segregation ratio in a the low proportion of affected sibs. recessive gene could obviously result in a distorted segregation ratio. parents who have had an affected child with low segregation ratio is that the disease is not The explanation of the low segregation ratio in Low segregation ratios in autosomal recessive disorders	./cache/work_5qjmgtplsfgdlgfs6d53glkdw4.pdf	./txt/work_5qjmgtplsfgdlgfs6d53glkdw4.txt