id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_5rbnj6bfcjdgvh63hbe3rasgdu	E. Rampersaud	Identification of Novel Candidate Genes for Type 2 Diabetes From a Genome-Wide Association Scan in the Old Order Amish: Evidence for Replication From Diabetes-Related Quantitative Traits and From Independent Populations	2007.0	10	.pdf	application/pdf	10464	2135	85	OBJECTIVE—We sought to identify type 2 diabetes susceptibility genes through a genome-wide association scan (GWAS) in trait in nondiabetic individuals; 80 SNPs were nominally associated with type 2 diabetes in one of the three independent 100K highly associated with type 2 diabetes in our Amish case-control dataset based highly type 2 diabetes–associated SNPs for association with diabetes-related 1. Schematic diagram of analysis and SNP prioritization approach for a 100K type 2 diabetes GWAS in the Amish. Fifty SNPs most highly associated with type 2 diabetes from Amish GWAS SNPs associated with type 2 diabetes (P � 0.01) and at least one OGTT-derived trait (P � 0.01) in nondiabetic Amish subjects traits in nondiabetic Amish individuals, 2) external replication of type 2 diabetes associations in three independent SNPs with P � 0.01 for type 2 diabetes associations were tested for consistency in a sample of nondiabetic individuals (295 of whom	./cache/work_5rbnj6bfcjdgvh63hbe3rasgdu.pdf	./txt/work_5rbnj6bfcjdgvh63hbe3rasgdu.txt