id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_6mnmp6axxnbsdm4dr6jrlur4yi	Wendy Post	Associations between Genetic Variants in the NOS1AP (CAPON) Gene and Cardiac Repolarization in the Old Order Amish	2007.0	6	.pdf	application/pdf	3939	363	59	SNP rs10494366 explained 0.9% of QT interval variability, with an average genetic effect of 6.1 ms. study provides further evidence that NOS1AP variants influence QT interval and further validates the utility of genomewide association studies, a relatively new approach to gene to performing genetic association studies in the Amish. Genetic association studies in isolated populations are between NOS1AP and the QT interval to additional populations, and also strengthen the evidence for the potential utility of genome-wide association studies, a relatively new approach to gene discovery. In stage II of that study, which consisted of 300 individuals from each extreme of the QT interval disPost /Shen /Damcott /Arking /Kao /Sack / Two of the four NOS1AP SNPs were significantly associated with variation in adjusted QT interval, as shown Associations between NOS1AP SNPs and adjusted QT interval KORA S4 and F3 populations, and 39% in the Framingham Heart Study, in which association between NOS1AP 	./cache/work_6mnmp6axxnbsdm4dr6jrlur4yi.pdf	./txt/work_6mnmp6axxnbsdm4dr6jrlur4yi.txt