id author title date pages extension mime words sentences flesch summary cache txt work_6sr3x3uoijhajalrpkljbor6tm G F Pierce Impaired culture generated cytotoxicity with preservation of spontaneous natural killer-cell activity in cartilage-hair hypoplasia 1983.0 7 .pdf application/pdf 5649 551 59 OKT3Fcy+ low-affinity E+), and a significant decrease in thymic derived OKT3+ cytolytic T cell subpopulations in CHH individuals. cellular cytotoxic effector mechanism has been identified in CHH (i.e., NK activity). However, allogeneic culture induced specific and NK-like cytotoxicity were markedly diminished in CHH. In contrast, minimal MLR-induced specific cell mediated lympholysis could be generated in CHH individuals (4.6±2.1% at E/T 30:1), whereas PBMC from Thus, CHH individuals showed a markedly decreased specific CML, as well as NK-like cytotoxicity The generation of radioresistant NK-like and specific cytotoxicity was correlated with allogeneic MLR-induced proliferation in seven CHH and normal individuals (proliferation vs. Radiation Resistance of NK-like Activity in CHH and Normal Individuals Culture-induced specific and NK-like cytotoxicity mediated by OKT3+ T-cells is proliferation cytotoxicity is mediated by the OKT3+ T5/T8+ T lymphocyte subpopulation (12-14), whereas the phenotype of the cells mediating NK-like culture-induced Cytotoxicity by cultured human lymphocytes: Characteristics of effector cells and specificity ./cache/work_6sr3x3uoijhajalrpkljbor6tm.pdf ./txt/work_6sr3x3uoijhajalrpkljbor6tm.txt