id author title date pages extension mime words sentences flesch summary cache txt work_f63rc2wk2jadfbwop3uagvd27m Coleen M. Damcott Polymorphisms in the Transcription Factor 7-Like 2 (TCF7L2) Gene Are Associated With Type 2 Diabetes in the Amish 2006.0 6 .pdf application/pdf 5149 499 69 (TCF7L2) Gene Are Associated With Type 2 Diabetes in identified in Icelandic individuals that showed strong association with type 2 diabetes, which was replicated in Danish We compared genotype frequencies in subjects with type 2 diabetes with those with NGT also genotyped these SNPs in nondiabetic, non-Amish subjects (n � 48), in whom intravenous glucose tolerance tests Using this combined case group, we found that the genotype frequencies of rs7901695 and rs7903146 differed significantly between type 2 diabetic/IGT subjects and NGT and rs1196205 SNPs showed marginal differences in genotype frequency between the type 2 diabetes/IGT and NGT Allele frequencies and results of association analysis in Amish subjects with type 2 diabetes, IGT, and NGT* for SNPs in TCF7L2 assessment of insulin resistance by genotype in nondiabetic Amish subjects (n � 698) for each TCF7L2 SNP SNPs in TCF7L2 and the type 2 diabetes/IGT trait in the ./cache/work_f63rc2wk2jadfbwop3uagvd27m.pdf ./txt/work_f63rc2wk2jadfbwop3uagvd27m.txt