id author title date pages extension mime words sentences flesch summary cache txt work_gpcf4nnd7jfabgh3brn4ysjnfq A. Malhotra Meta-Analysis of Genome-Wide Linkage Studies of Quantitative Lipid Traits in Families Ascertained for Type 2 Diabetes 2007.0 7 .pdf application/pdf 5590 1546 81 families ascertained for type 2 diabetes, individually yielding linkage results that were largely nonoverlapping. and, together with the results of this meta-analysis, provide compelling evidence that these regions harbor important determinants of lipid levels in individuals with type 2 population (10) and for triglyceride/HDL levels in Caucasian families from the GENNID Study (3). families ascertained for type 2 diabetes and lack of statistically significant evidence for linkage can result from both Genome Scan Meta-Analysis; HKFDS, Hong Kong Family Diabetes Study; meta-analysis of linkage results for quantitative lipid traits We performed a meta-analysis for the following quantitative lipid traits: LDL (seven studies), HDL (nine The strongest evidence of linkage for lipid traits identified in this study was found on chromosomes 7 and 19. A statistically significant P value identified in this meta-analysis, combined with multiple observations of linkage in unrelated studies, supports the traits in familial type 2 diabetes: evidence for linkage of triglyceride levels ./cache/work_gpcf4nnd7jfabgh3brn4ysjnfq.pdf ./txt/work_gpcf4nnd7jfabgh3brn4ysjnfq.txt