id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_hq6a2krvgfcuvo3ktdoccddonu	T. I. Pollin	Linkage of Plasma Adiponectin Levels to 3q27 Explained by Association With Variation in the APM1 Gene	2004.0	7	.pdf	application/pdf	6630	555	64	the 3� untranslated region (single nucleotide polymorphism [SNP] �2019; deletion allele frequency 0.30 in Amish) showed strong association with adiponectin levels in a dosage-dependent manner in a direction consistent with that reported in previous studies, with variation in APM1 is responsible for linkage of adiponectin levels to 3q27 in the Old Order Amish. associated with diabetes (16) and other metabolic syndrome features, as well as with adiponectin levels themselves (16 –18). quantitative trait locus; SNP, single nucleotide polymorphism; SOLAR, Sequential Oligogenic Linkage Analysis Routines; UTR, untranslated region. environmental covariates, the additive effects of genes (i.e., residual heritability), and a specific quantitative trait locus (QTL, the linkage component). we estimated the effects of the SNP genotype on adiponectin levels, adjusting Association of six APM1 SNPs with adiponectin levels The highest LOD score, 2.13, was observed in the region containing APM1, the adiponectin structural gene. LINKAGE AND ASSOCIATION OF ADIPONECTIN LEVELS	./cache/work_hq6a2krvgfcuvo3ktdoccddonu.pdf	./txt/work_hq6a2krvgfcuvo3ktdoccddonu.txt