id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_ikfvovri6ve7djhhj2k3ct3ooe	Reihaneh Alikhani	Investigating Seven Recently Identified Genes in 100 Iranian Families with Autosomal Recessive Non-syndromic Hearing Loss	2015.0	5	.pdf	application/pdf	3018	362	67	Investigating Seven Recently Identified Genes in 100 Iranian Families (GJB4, GJC3, and SLITRK6) reported in neighboring countries among Iranian families with ARNSHL. Methods: One hundred unrelated families with at least two affected siblings in consanguineous marriage, who were negative for GJB2 gene mutations, were selected. Discussion: These data demonstrate a very low prevalence of mutation in these three genes (GJB4, GJC3, and SLITRK6) in the Iranian population, since no mutation was detected in our study group of 100 Keywords: Autosomal recessive non-syndromic hearing loss, homozygosity mapping, linkage analysis, three new HL genes (GJB4, GJC3, and SLITRK6). The candidate genes, their locations, the reported linked families in different countries. Gene Chromosome Locus Country Mutation References the three genes, GJB4, GJC3, or SLITRK6, after No. Locus Gene No. of linked families Clinical features STR Markers three different genes (GJB4, GJC3, and SLITRK6) the connexin gene family as a cause of nonsyndromic 	./cache/work_ikfvovri6ve7djhhj2k3ct3ooe.pdf	./txt/work_ikfvovri6ve7djhhj2k3ct3ooe.txt