id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_msxl2u2kc5aoja6idaufwya47e	Amish Shah	Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response	2009.0	13	.pdf	application/pdf	5882	518	55	(PKR), limits late viral protein synthesis and replication of 134.5 viruses. protein product encoded by the HSV 134.5 gene that counters this host antiviral response, the review this defense is protein kinase R (PKR), which limits viral gene expression and replication in human encoded within the 3' gene domain, blocks host PKR-mediated protein shutoff during infection thus allowing continued late viral protein synthesis in infected cells [13]. In contrast, viruses capable of PKR evasion and late viral protein synthesis In tumor cells infected with recombinants capable of late viral protein synthesis, gD virus capable of continued viral protein translation in infected SK-N-SH cells [33]. The progeny virus expressed US11 earlier in infection, exhibited a wildtype protein synthesis phenotype, and was found in in vivo studies to partially restore HSV protein of herpes simplex virus type 1 is required for viral response to interferon but is not 	./cache/work_msxl2u2kc5aoja6idaufwya47e.pdf	./txt/work_msxl2u2kc5aoja6idaufwya47e.txt