id author title date pages extension mime words sentences flesch summary cache txt work_r4y7i7xkmfchzmeo3aurckyu6a Patrick F McArdle Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference 2012.0 7 .pdf application/pdf 5816 659 46 Background: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). and CVD risk factors, including obesity, cholesterol, measures of vascular function and blood pressure. Results: Serum bilirubin levels were inversely associated with levels of several cardiovascular disease risk factors, reported associations of serum bilirubin levels to cardiovascular disease risk factors, including total cholesterol In this study, we describe use of the Mendelian randomization approach to evaluate relations of serum bilirubin levels with CVD risk factors and subclinical bilirubin levels and CVD risk factors without consideration for UGT1A1*28 genotype with the presumed Mendelian randomization estimate of the serum bilirubin-CVD risk factor correlation was obtained by dividing Estimates of associations of CVD risk factors with bilirubin and with UGT1A1*28 genotype were evaluated Association of serum Bilirubin levels with CVD risk factors Association of serum Bilirubin levels with CVD risk factors Association of serum Bilirubin levels with CVD risk factors: Mendelian randomization approach ./cache/work_r4y7i7xkmfchzmeo3aurckyu6a.pdf ./txt/work_r4y7i7xkmfchzmeo3aurckyu6a.txt