id author title date pages extension mime words sentences flesch summary cache txt work_vmslbui6v5he5a4dunbicn7j6u Michael Zeisberg Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney 2004.0 7 .pdf application/pdf 6492 521 56 BMP-7 inhibits epithelial-mesenchymal transition involving adult renal epithelial tubular cells and decreases secretion of type I collagen by adult renal fibroblasts. kidney, tubular epithelial cells can convert into fibroblast via 2. Regulation of E-cadherin expression by BMP-7 in adult renal fibroblasts. C, adult renal fibroblasts were treated with BMP-7, and the expression of E-cadherin, Pax2, and Wnt4 was analyzed by immunoblot. Immunocytochemistry analysis of BMP-7-treated fibroblasts revealed that cells within the aggregated/condensed areas expressed abundant levels of the epithelial marker E-cadherin (Fig. 1F) and cytokeratin (data not shown) as compared Formation of E-cadherin-expressing epithelial cell aggregates, as observed in our studies, mimics BMP-7-mediated BMP-7 inhibits EMT involving adult renal epithelial cells, we Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney* Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney* ./cache/work_vmslbui6v5he5a4dunbicn7j6u.pdf ./txt/work_vmslbui6v5he5a4dunbicn7j6u.txt