id author title date pages extension mime words sentences flesch summary cache txt work_x3vzjebhcvf6leinyi3nj23rnu W.-C. Hsueh Genome-Wide and Fine-Mapping Linkage Studies of Type 2 Diabetes and Glucose Traits in the Old Order Amish: Evidence for a New Diabetes Locus on Chromosome 14q11 and Confirmation of a Locus on Chromosome 1q21-q24 2003.0 8 .pdf application/pdf 8260 690 67 search for genes linked to type 2 diabetes in 691 individuals from a founder population, the Old Order Amish. our findings provide evidence that type 2 diabetes susceptibility genes reside on chromosomes 1, 14, and 18. recently, researchers have turned to genome-wide approaches for identifying genes linked to type 2 diabetes [IGH]) and quantitatively distributed traits related to diabetes (plasma glucose levels and HbA1c), and we used IGH, to test for interactions between genomic regions (the type 2 diabetes trait 1p, evidence for linkage to the discrete type 2 diabetes trait On chromosome 14, we also observed increased evidence supporting linkage using a denser genetic map. type 2 diabetes/IGH trait at three regions that had LOD Chromosomal regions showing evidence for linkage, with a LOD � 1.18 (P � 0.01), to diabetes and related traits using 373 framework 1. Multipoint linkage analysis results of glucose and diabetes for chromosomes 1 and 14 in the ./cache/work_x3vzjebhcvf6leinyi3nj23rnu.pdf ./txt/work_x3vzjebhcvf6leinyi3nj23rnu.txt