id author title date pages extension mime words sentences flesch summary cache txt work_ysllfxwnx5bsrc5tl73uiq4qcm J. H. Edwards Caution in locating the gene(s) for affective disorder1 1989.0 3 .pdf application/pdf 2165 139 60 The familial aggregation of cases has long been held to indicate a major genetic factor in manicdepressive disorders but this information has not been sufficient to be of practical use clinically. LINKAGE BETWEEN A DISEASE GENE LOCUS AND A MARKER If linkage can be established by a consistent tendency to cosegregation between a marker gene and showed transmission of affective disorder, was the subject of the linkage studies carried out by calculation in the first study for the use of a large number of markers (20), as opposed to a single The second is that the first round of linkage tests defined a set of cosegregating segments of DNA Whereas in linkage studies the problem is the number of loci at which markers Construction of a genetic linkage map in man using restriction HLA antigens in affective disorders and schizophrenia. Bipolar affective disorders linked to DNA markers on chromosome interval under possible heterogeneity. ./cache/work_ysllfxwnx5bsrc5tl73uiq4qcm.pdf ./txt/work_ysllfxwnx5bsrc5tl73uiq4qcm.txt