id author title date pages extension mime words sentences flesch summary cache txt work_z53rgrucjrbcvh2bkhuihqvare H. Wang Effect of Two Lipoprotein (a)-Associated Genetic Variants on Plasminogen Levels and Fibrinolysis 2016.0 8 .pdf application/pdf 6215 611 62 Finally, plasminogen mRNA expression in liver samples derived from 76 Caucasian subjects was not significantly different between carriers and noncarriers of these two genetic variants. and show that these polymorphisms are not major modulating factors for plasma plasminogen levels and In addition, single nucleotide polymorphisms (SNPs) in the LPA gene are associated with Lp(a) levels. Indeed, a recently published study by our group has provided additional evidence that these variants are significantly associated with To evaluate whether LPA genetic variants affect plasma plasminogen between the carriers and noncarriers of the two LPA genetic variants Association between LPA genetic variants and plasma Figure 3 Plasma plasminogen levels among the OOA subjects for the plasminogen levels, we investigated whether LPA SNPs rs3798220 Consistent with previous studies, the plasma Lp(a) levels were significantly higher for carriers of genetic determinants of plasma plasminogen levels. variants associated with Lp(a) lipoprotein level and coronary disease. ./cache/work_z53rgrucjrbcvh2bkhuihqvare.pdf ./txt/work_z53rgrucjrbcvh2bkhuihqvare.txt