id author title date pages extension mime words sentences flesch summary cache txt work_zgn3gbcvwrgkplxr3ggorlzsuy Amish Acharya Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis 2016.0 10 .pdf application/pdf 7070 638 55 Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis Background Acute appendicitis is the most common surgical emergency and can represent a challenging diagnosis, biomarkers associated with appendicitis to more appropriately assign risk and allocate further diagnostic investigation. WCC White cell count, CRP C-reactive protein, IL-6 Interleukin 6, 5-HIAA Urinary serotonin, Sens Sensitivity, Spec Specificity The pooled sensitivity of C-reactive protein for the diagnosis of acute appendicitis was 0.76 (95 % CI 0.75–0.78; diagnostic ability of the biomarker with respect to suspected appendicitis and can spuriously improve the specificity. Table 3 Normalized scores (out of 100) for the six biomarkers with respect to financial cost, time, diagnostic benefit (composite of sensitivity, In fact, no single biomarker had all the desired characteristics for the diagnosis of acute appendicitis. diagnostic value of procalcitonin in patients with acute appendicitis. Biomarkers of acute appendicitis: systematic review and cost--benefit trade-off analysis ./cache/work_zgn3gbcvwrgkplxr3ggorlzsuy.pdf ./txt/work_zgn3gbcvwrgkplxr3ggorlzsuy.txt