Manic Depressive Illness and Tyrosine Hydroxylase Gene: Linkage Heterogeneity and Association | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1006/NBDI.1997.0149 Corpus ID: 10880668Manic Depressive Illness and Tyrosine Hydroxylase Gene: Linkage Heterogeneity and Association @article{Malafosse1997ManicDI, title={Manic Depressive Illness and Tyrosine Hydroxylase Gene: Linkage Heterogeneity and Association}, author={A. Malafosse and M. Leboyer and T. d'Amato and S. Amad{\'e}o and J. Mallet}, journal={Neurobiology of Disease}, year={1997}, volume={4}, pages={337-349} } A. Malafosse, M. Leboyer, +2 authors J. Mallet Published 1997 Psychology, Medicine Neurobiology of Disease Several studies have implicated the tyrosine hydroxylase (TH) locus within the 11p15 region in susceptibility to manic depressive illness (MDI). This possibility was further investigated by both parametric (lod score) and nonparametric (affected-pedigree-member and a case-control study) methods of analysis in 11 French MDI families and in a sample of 200 unrelated subjects. Both types of analyses corroborate the implication of this locus, and positive lod scores were obtained in two families… Expand View on Elsevier doi.org Save to Library Create Alert Cite Launch Research Feed Share This Paper 22 CitationsHighly Influential Citations 1 Background Citations 10 Methods Citations 1 Results Citations 1 View All Topics from this paper Bipolar Disorder TH gene Depressive disorder 11p15 Genetic Heterogeneity Mixed Function Oxygenases Scientific Publication 22 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Linkage of mood disorders with D2, D3 and TH genes: a multicenter study. A. Serretti, F. Macciardi, +20 authors J. Mendlewicz Psychology, Medicine Journal of affective disorders 2000 32 Save Alert Research Feed Analysis and metaanalysis of two polymorphisms within the tyrosine hydroxylase gene in bipolar and unipolar affective disorders. R. Furlong, J. Rubinsztein, +6 authors D. Rubinsztein Medicine American journal of medical genetics 1999 63 Save Alert Research Feed Multicentre Italian family‐based association study on tyrosine hydroxylase, catechol‐O‐methyl transferase and Wolfram syndrome 1 polymorphisms in mood disorders A. Serretti, C. Cusin, +9 authors G. Nappi Psychology, Medicine Psychiatric genetics 2003 34 View 2 excerpts, cites background Save Alert Research Feed Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4 P. Muglia, A. Petronis, E. Mundo, S. Lander, T. Cate, J. L. Kennedy Biology, Medicine Molecular Psychiatry 2002 62 PDF Save Alert Research Feed No Evidence of an Association Between Tyrosine Hydroxylase Gene Polymorphisms and Suicide Victims HARUKI HATTORI H. Nushida, K. Maeda 2006 PDF View 1 excerpt, cites background Save Alert Research Feed No evidence of an association between tyrosine hydroxylase gene polymorphisms and suicide victims. H. Hattori, O. Shirakawa, N. Nishiguchi, H. Nushida, Y. Ueno, K. Maeda Medicine The Kobe journal of medical sciences 2006 9 View 1 excerpt, cites background Save Alert Research Feed Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorder. L. Ho, R. Furlong, J. Rubinsztein, C. Walsh, E. Paykel, D. Rubinsztein Medicine American journal of medical genetics 2000 100 Save Alert Research Feed Searching high and low: a review of the genetics of bipolar disorder. J. Potash, J. Depaulo Psychology, Medicine Bipolar disorders 2000 74 Save Alert Research Feed Post-genomic era and gene discovery for psychiatric diseases: There is a new art of the trade? R. Meloni, N. F. Biguet, J. Mallet Biology, Medicine Molecular Neurobiology 2007 11 Save Alert Research Feed Chapter 5.1 sychiatric genetics current perspective D. Levinson Psychology 1999 Save Alert Research Feed ... 1 2 3 ... References SHOWING 1-10 OF 43 REFERENCES SORT BYRelevance Most Influenced Papers Recency Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German‐British sample of manic depressive patients and controls J. Körner, M. Rietschel, +10 authors P. Propping Biology, Medicine Psychiatric genetics 1994 33 Save Alert Research Feed Absence of linkage between chromosome 11p15 markers and manic-depressive illness in a Belgian pedigree. J. Mendlewicz, M. Leboyer, +5 authors J. Mallet Biology, Medicine The American journal of psychiatry 1991 51 Save Alert Research Feed Linkage between tyrosine hydroxylase gene and affective disorder cannot be excluded in two of six pedigrees. L. Lim, H. Gurling, D. Curtis, J. Brynjólfsson, H. Petursson, M. Gill Biology, Medicine American journal of medical genetics 1993 53 Save Alert Research Feed RFLP alleles at the tyrosine hydroxylase locus: No association found to affective disorders J. Körner, J. Fritze, P. Propping Biology, Medicine Psychiatry Research 1990 48 Save Alert Research Feed Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. W. Berrettini, T. Ferraro, +4 authors E. Gershon Biology, Medicine Proceedings of the National Academy of Sciences of the United States of America 1994 343 PDF Save Alert Research Feed Molecular genetic evidence for heterogeneity in manic depression S. Hodgkinson, R. Sherrington, +6 authors J. Brynjólfsson Biology, Medicine Nature 1987 250 Save Alert Research Feed Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees S. Detera-Wadleigh, W. Berrettini, L. Goldin, D. Boorman, Stewart Anderson, E. Gershon Biology, Medicine Nature 1987 215 Save Alert Research Feed A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3 R. Straub, T. Lehner, +12 authors M. Baron Biology, Medicine Nature Genetics 1994 298 Save Alert Research Feed Tyrosine hydroxylase gene not linked to manic-depression in seven of eight pedigrees. W. Byerley, R. Plaetke, +7 authors M. Leppert Biology, Medicine Human heredity 1992 53 Save Alert Research Feed Approaches to the genetics of affective disorders. N. Craddock, P. McGuffin Psychology, Medicine Annals of medicine 1993 30 View 1 excerpt, references background Save Alert Research Feed ... 1 2 3 4 5 ... 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