id author title date pages extension mime words sentences flesch summary cache txt work_2rtnpmeiufhmtossl5b2s3pgg4 Junichi Sadoshima Cardiac fibroblasts: The good, the bad, the ugly, the beautiful 2014 2 .pdf application/pdf 661 61 54 Weiss, James N https://escholarship.org This special issue is focused on the role of fibroblasts in cardiac biology. Fibroblasts are the most numerous cells in the heart, and although Not only do fibroblasts play a key role in cardiac development, but once cells that are continuously reshaping the extracellular matrix to optimize the contractile function of the myocytes embedded within that Fibroblast biology will play a critical role in attempts to regenerate cardiac are challenging issues, as the biology of cardiac fibroblasts is complex Accordingly, the goal of this special issue is to provide a state-of-theart update on fibroblast biology as it relates to the heart. cardiac development, to maintaining the adult heart in a healthy state, first focusing on the cell biology of fibroblasts and myofibroblasts in http://dx.doi.org/10.1016/j.yjmcc.2014.03.009 Finally, the last two articles focus on the therapeutic potential of modulating fibroblast biology. http://www.sciencedirect.com/science/journal/00222828 ./cache/work_2rtnpmeiufhmtossl5b2s3pgg4.pdf ./txt/work_2rtnpmeiufhmtossl5b2s3pgg4.txt