id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_dlihjrrvavaorf4r4g2icz65cq	Suneel A. Narayanavari	Sleeping Beauty transposition: from biology to applications	2016	28	.pdf	application/pdf	18530	2219	60	Sleeping Beauty (SB) is the first synthetic DNA transposon that was shown to be active in a wide transposons (Plasterk et al., 1999) comprising a transposase gene flanked by inverted repeats (IRs) containing recognition sequences for transposase binding co-crystal containing the substrate DNA with transposase, the authors generated an in silico transposon capture complex (TCC) model. SB can be optimized for stable transgene expression (gene/cell therapy, germ line transgenesis). integration, the hybrid AAV/transposon (SB100X) provides sustained gene expression (Zhang et al., 2013), induced pluripotent stem cells from human fetal fibroblasts using the Sleeping Beauty transposon gene delivery genomes of human cells by the sleeping beauty transposon system. Sleeping Beauty transposon system for genetic etiological research and gene Sleeping Beauty transposons rapidly generate stable transgenic cell lines. and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells. Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.	./cache/work_dlihjrrvavaorf4r4g2icz65cq.pdf	./txt/work_dlihjrrvavaorf4r4g2icz65cq.txt