id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_g7oghq6ba5hnzhss6pyxeoiet4	Conrad A Vink	Sleeping Beauty Transposition From Nonintegrating Lentivirus	2009		.pdf	text/html	1076	215	59	Lentiviral vectors enter cells with high efficiency and deliver stable transduction through integration into host chromosomes, but their preference for integration within actively transcribing genes means that insertional mutagenesis following disruption of host proto-oncogenes is a recognized concern. We have addressed this problem by combining the efficient cell and nuclear entry properties of HIV-1-derived lentiviral vectors with the integration profile benefits of Sleeping Beauty (SB… Expand Sort by Most Influenced Papers Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells. A hybrid lentivirus-transposon vector for safer gene therapy Development of the hybrid Sleeping Beauty-baculovirus vector for sustained gene expression and cancer therapy Effective gene therapy with nonintegrating lentiviral vectors Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon. Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI.	./cache/work_g7oghq6ba5hnzhss6pyxeoiet4.pdf	./txt/work_g7oghq6ba5hnzhss6pyxeoiet4.txt