id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_noarukcrlvftjjqmmjug7afrze	J. V. Gray	"Sleeping Beauty": Quiescence in Saccharomyces cerevisiae	2004	20	.pdf	application/pdf	21793	2761	65	Quiescent yeast cells are commonly obtained in the laboratory by growing liquid cultures to saturation in rich media, The cell quiescence cycle is the process by which nutrient limitation (e.g., carbon starvation in our reference case) causes exit quiescence; and the protein kinase C (PKC) and Snf1p pathways, apparent positive activators of the transition (Fig. 3). yeast cells appear to enter a quiescence-like state (3). (126) and Cox6p (176) in proliferating cells, suggesting a possible role for the pathway in regulating carbohydrate metabolism and mitochondrial function at the diauxic shift. Thus, the signaling pathways thought to regulate entry into quiescence appear to form an interacting network that acts at the diauxic shift in response to the change in the regulation of protein turnover in quiescent yeast cells. Evidence from mutants clearly implicates ubiquitin-dependent protein degradation as a process essential for the maintenance of viability in quiescent cells.	./cache/work_noarukcrlvftjjqmmjug7afrze.pdf	./txt/work_noarukcrlvftjjqmmjug7afrze.txt