id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_oninjsyusjhrbgn2jfns3o4u4q	Kai-Jye Lou	Sleeping Beauty gets specific	2009	2	.pdf	application/pdf	1165	97	48	inability to generate tumors in a tissue-specific manner made it difficult to track the origins of a particular cancer cell. developing the Sleeping Beauty system for use in human gene therapy. activity of the Sleeping Beauty transposon to specific organs and tissues," said Perry Hackett, a professor in the university's Department National Cancer Institute showed that an earlier iteration of the Sleeping Beauty system caused mice to rapidly succumb to hematopoietic Anton Berns, director of research at the Netherlands Cancer Institute, said the data generated from Sleeping Beauty–based insertional With the two proof-of-concept studies from Largaespada's group supporting use of the Sleeping Beauty system in cancer gene discovery, For example, Berns said, the Sleeping Beauty system cannot generate activating point mutations in genes like Ras, which are known to Largaespada said his group is using Sleeping Beauty to identify Beauty transposon system to identify cancer genes in laboratory animals 	./cache/work_oninjsyusjhrbgn2jfns3o4u4q.pdf	./txt/work_oninjsyusjhrbgn2jfns3o4u4q.txt