id author title date pages extension mime words sentences flesch summary cache txt work_ozxprpobdngxhl77hvg5dyhnou Giandomenico Turchiano Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells 2014 11 .pdf application/pdf 9007 792 58 The Sleeping Beauty (SB) transposon is a non-viral integrating vector system with proven efficacy for gene transfer and Clonal analysis of SA integrants in human epithelial cells and in immortalized keratinocytes demonstrates stability and integrity of the transposon independently from the cargo size and copy number-dependent (2014) Genomic Analysis of Sleeping Beauty Transposon Integration in Human Finally, high-resolution, genome-wide mapping of SA integrations in human keratinocytes revealed a close-torandom integration pattern with respect to genes and chromosomes, highlighting a relative low risk of genotoxicity as previously Molecular characterization of the Sleeping Beauty-mediated integration events in GABEB cell clones. analysis of genomic DNA from GABEB cell clones digested with NheI (SA clones) or AflII (T2 clones), single cutter in the transposon cassette, and and expression in human primary T cells by the Sleeping Beauty transposon (2014) Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells. Transposon Integration in Human Somatic Cells. ./cache/work_ozxprpobdngxhl77hvg5dyhnou.pdf ./txt/work_ozxprpobdngxhl77hvg5dyhnou.txt