id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_qlfchymhsrgv5gjmnyfv3kvfhi	Helen A. Fletcher	Sleeping Beauty and the Story of the Bacille Calmette-Guérin Vaccine	2016	3	.pdf	application/pdf	2857	403	62	ABSTRACT Mycobacterium bovis BCG is the only available vaccine for protection against tuberculosis (TB). (strain VPM1002) is in advanced clinical trials and shows promise for improved vaccine safety but little change in efficacy in animal models. A second-generation recombinant BCG vaccine with an additional deletion of the nuoG gene (BCG �ureC::hly like Sleeping Beauty pricked by the spinning wheel, we have slept for 100 years, showing a reluctance to invest in clinical development or in biomanufacturing capacity for TB vaccines. and call us to invest in new-generation TB vaccines and to protect the biomanufacture of our current BCG vaccine. http://www.tbvi.eu/wp-content/uploads/2016/02/Grode_SII-VPM-Status-on-TB-vaccine-150318.pdf http://www.tbvi.eu/wp-content/uploads/2016/02/Grode_SII-VPM-Status-on-TB-vaccine-150318.pdf http://www.tbvi.eu/wp-content/uploads/2016/02/Grode_SII-VPM-Status-on-TB-vaccine-150318.pdf clinical disease, VPM1002 will be the first new TB vaccine to enter have slumbered for 100 years with the current BCG vaccine, showing a reluctance to invest in clinical development and neglecting IMPACT OF A NEW RECOMBINANT BCG VACCINE ON THE DEVELOPMENT OF VPM1002	./cache/work_qlfchymhsrgv5gjmnyfv3kvfhi.pdf	./txt/work_qlfchymhsrgv5gjmnyfv3kvfhi.txt