id author title date pages extension mime words sentences flesch summary cache txt work_x2ddxaksnjbjxo44s5jg2i4jzm I. P. Hall The genetics of obstructive lung disease: big is beautiful 2010 2 .pdf application/pdf 2473 375 65 Chronic obstructive pulmonary disease heritable factors play a role in the pathogenesis of this disease.2 3 The only genetic associated with COPD is severe deficiency of a1-antitrypsin. genetic factors that predispose to COPD in now the case with candidate gene studies genome-wide association studies (GWAS) (IREB2).17 This was identified by expression analysis in lung tissue from individuals with COPD and then confirmed in intensity, airflow obstruction and emphysema,20 21 SNPs in the hedgehog interacting protein are associated with systemic identify more genes that are associated size of individual SNPs for asthma risk has cohort for risk SNPs in these genes A genomewide association study in chronic obstructive pulmonary disease (COPD): identification of two identify multiple loci associated with pulmonary chronic obstructive pulmonary disease is associated Am J Respir Crit Care Med Am J Respir Crit Care Med Am J Respir Crit Care Med Am J Respir Crit Care Med ./cache/work_x2ddxaksnjbjxo44s5jg2i4jzm.pdf ./txt/work_x2ddxaksnjbjxo44s5jg2i4jzm.txt