id author title date pages extension mime words sentences flesch summary cache txt work_y54z4egsqnawtf5ezrqfrtllim Xuri Li VEGF-B: a thing of beauty 2010 4 .pdf application/pdf 2328 201 62 endothelial growth factor B (VEGF-B), energy metabolism demand, such as skeletal muscles, cardiac myocytes and brown adipose tissues (BATs), express high Upon binding to VEGFR-1 and Nrp-1 expressed by the vascular endothelial cells, VEGF-B upregulates the expression of fatty acid transport proteins (FATPs). The FATPs transport the fatty acids from blood stream across the endothelium to peripheral tissues for energy production. Importantly, as a result of the impaired FA transport and utilization, the unconsumed FA are accumulated in the white adipose tissues (WATs), resulting in greater body fat mass and weight in the VEGF-B The biological consequences of the impaired FA uptake in the VEGF-B deficient hearts, muscles and BATs remain It is also unknown whether the reported survival/antiapoptotic effect of VEGF-B is linked to its FA-transport function. In addition, it remains to be studied why VEGF-B deficiency does not blunt FA uptake in the WATs, while this is true in other ./cache/work_y54z4egsqnawtf5ezrqfrtllim.pdf ./txt/work_y54z4egsqnawtf5ezrqfrtllim.txt