id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2021_01_04_425177	Gielnik, Maciej	The engineered peptide construct NCAM1-Aβ inhibits aggregation of the human prion protein (PrP)	2021	12	.pdf	application/pdf	4668	458	64	The engineered peptide construct NCAM1-Aβ inhibits aggregation of the human prion protein (PrP) aggregation of the human prion protein (PrP) engineered cell-penetrating peptide constructs can reduce the amount of prion Udgaonkar, 2018; Verma et al., 2015), such as the prion (PrP) protein (CreutzfeldtJakob disease), α-synuclein (Parkinson's disease), and amyloid-β (Aβ) and tau As the NCAM1-Aβ construct inhibits fibrillation of the Aβ peptide (HenningKnechtel et al., 2020), but promotes (co-)aggregation of the S100A9 protein (Pansieri huPrP protein + 0.5 µM NCAM1-Aβ peptide, incubated for 72 hours. between NCAM1-Aβ and S100A9 protein, where amyloid aggregation is promoted might affect the aggregation of other disease-related prion proteins, such as those prion aggregates in infected cells, is that these peptide constructs directly interact with properties of prion protein-derived cell-penetrating peptides. Cytotoxicity of prion protein-derived cell-penetrating peptides is modulated by pH ProInflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs. Formation and properties of amyloid fibrils of prion protein.	./cache/10_1101-2021_01_04_425177.pdf	./txt/10_1101-2021_01_04_425177.txt