id author title date pages extension mime words sentences flesch summary cache txt cord-276874-9rjbmsvb Ng, M.L. Topographic Changes in SARS Coronavirus–infected Cells at Late Stages of Infection 2004-11-17 .txt text/plain 3172 188 52 Scanning electron and atomic force microscopy was used for the first time to view the maturation of the severe acute respiratory syndrome–associated coronavirus at the cell surface. Scanning electron and atomic force microscopy was used for the first time to view the maturation of the severe acute respiratory syndrome-associated coronavirus at the cell surface. High magnification of the maturing virus particles showed a rosette appearance with short knoblike spikes under both the scanning electron and atomic force microscopes. High magnification of the maturing virus particles showed a rosette appearance with short knoblike spikes under both the scanning electron and atomic force microscopes. The aim of this study was to use scanning electron and atomic force microscopes to investigate changes in the surface topography of SARS-CoV-infected cells at late infection. Scanning electron microscopy of Vero E6 cells infected with severe acute respiratory syndrome-associated coronavirus at 24 h after infection. ./cache/cord-276874-9rjbmsvb.txt ./txt/cord-276874-9rjbmsvb.txt