id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-307968-sqe7h05t	Alfano-Sobsey, Edith M.	Human Challenge Pilot Study with Cyclospora cayetanensis	2004-04-17		.txt	text/plain	1581	98	46	We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. In addition, data from Cryptosporidium human volunteer studies demonstrated that the 50% infectious dose (ID 50 ) differed (from 9 to 1,042 oocysts), depending on the isolate used in the study (10) . For these reasons, we attempted to vary the inocula by selecting oocysts from persons in different geographic regions (Haiti, Missouri, and Georgia) and increasing the numbers All oocysts in stool samples in this study were stored in potassium dichromate (2.5%), and most of the final inoculum preparations were disinfected with bleach (5.25%). Cryptosporidium parvum has been stored in 2.5% potassium dichromate (for <6 weeks to >12 weeks) and remained infectious in human volunteers, cell culture, and animals (11, 12) . However, the effects of potassium dichromate and bleach on the Cyclospora oocysts used in this study are unknown, since methods to evaluate infectivity and viability were not available.	./cache/cord-307968-sqe7h05t.txt	./txt/cord-307968-sqe7h05t.txt