id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350513-ho32ajsx	Chen, Paul Chih‐Hsueh	Re: To KF, Tong JH, Chan PK, et al. Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in‐situ hybridization study of fatal cases. J Pathol 2004; 202: 157–163	2004-05-07		.txt	text/plain	1099	63	49	Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in‐situ hybridization study of fatal cases. Using in situ hybridization (ISH), To et al demonstrated the presence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in pneumocytes and in the surface enterocytes of the small intestine. Supplementing their findings, we report here our recent study, which suggests that the SARS-CoV may not be exclusively located in pneumocytes, but also in pulmonary macrophages. Under low magnification, scattered cells containing dark bluish signals, which represented the SARS-CoV, were visualized ( Figure 1A , nuclear fast red counterstain) within the damaged alveolar spaces, small bronchioles, and even the vascular lumina. Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases Chen and Hsiao make an interesting observation on the pathology of severe acute respiratory syndrome (SARS).	./cache/cord-350513-ho32ajsx.txt	./txt/cord-350513-ho32ajsx.txt