id author title date pages extension mime words sentences flesch summary cache txt cord-256550-72i1x02f Klotz, Lynn C. Danger of Potential-Pandemic-Pathogen Research Enterprises 2015-06-16 .txt text/plain 3228 161 59 Concern over escape from a laboratory of a deadly human-contagious virus (e.g., influenza, severe acute respiratory syndrome [SARS] , and Middle East respiratory syndrome [MERS] viruses) prompted the U.S. Government to hold back funding for this research "until a robust and broad deliberative process (2) is completed that results in the adoption of a new USG gain-of-function research policy." This discussion is now under way in the United States and is to be completed in 2016. Defending the safety of his work in the first letter (3), Dr. Fouchier calculated that it would likely take more than a million years for an escape from his lab through a laboratory-acquired infection (LAI). If P 1 is really as low as Fouchier suggests, we would need to wait 670 years to reach a 1% chance of escape, an elapsed time that would appear to make the research enterprise safe in some researchers' thinking, but risk equals likelihood times consequences, and consequences such as fatalities could be very high for a human-contagious influenza virus with a high case fatality rate. ./cache/cord-256550-72i1x02f.txt ./txt/cord-256550-72i1x02f.txt