id author title date pages extension mime words sentences flesch summary cache txt cord-275443-9ib77yws Xie, Xing Monoclonal antibody specific to HA2 glycopeptide protects mice from H3N2 influenza virus infection 2015-03-19 .txt text/plain 8280 392 56 Considering that mAb D7 resulted in a significant reduction in viral titers in the lungs of mice infected with three different virus strains at 6 dpi, we chose that time point to determine the viral RNA loads in different tissues and fecal samples. To compare the above results with pathological findings in mice infected with three different virus strains, and treated with mAb D7 and irrelevant mAb IgG, we chose the heart, brain and lung from different treatment groups at 6 dpi to perform histopathological and immunohistochemical analysis. To gain a better understanding of the effect of CIV on the innate immune response and to ascertain whether passive immunization with monoclonal antibody affected the levels of cytokines, we examined the levels of IFN-γ and TNF-α in the lungs of mice in the virus-infected and mAb D7 groups. ./cache/cord-275443-9ib77yws.txt ./txt/cord-275443-9ib77yws.txt