id author title date pages extension mime words sentences flesch summary cache txt cord-332317-wrztpeb8 Zhang, Xin Identification of the interaction between vimentin and nucleocapsid protein of transmissible gastroenteritis virus 2015-03-16 .txt text/plain 3977 241 49 Nucleocapsid (N) protein of transmissible gastroenteritis virus (TGEV) packages viral RNA genome to form a ribonucleoprotein complex. The present study thus provides protein-related information about interaction of TGEV N protein with host cell that should be useful for understanding host cell response to coronavirus pathogenesis infection and the underlying mechanism of coronavirus replication. Recently, some reports showed that N protein of TGEV play an important role in host cell for virus replication. Three cellular proteins, hnRNP U, ACTN4, and vimentin, were identified both by GST-N pull down and Co-IP in TGEV-infected cells, which should have more biological importance in the context of infection. The interaction between the cellular vimentin and N protein of TGEV was confirmed in TGEV-infected ST cells. Host cell proteins interacting with the 3 end of TGEV coronavirus genome influence virus replication EF1A interacting with nucleocapsid protein of transmissible gastroenteritis coronavirus and plays a role in virus replication ./cache/cord-332317-wrztpeb8.txt ./txt/cord-332317-wrztpeb8.txt