id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002985-2rtk9ppu	Pickett, Julie E.	Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone	2018-04-25		.txt	text/plain	5848	296	48	We then radiolabeled the anti-LTA mAb and evaluated its effectiveness as a diagnostic imaging tool for detecting infection via immunoPET imaging in an in vivo mouse model of prosthetic joint infection (PJI). The in vivo PJI mouse model was assessed using traditional imaging modalities, including positron emission tomography (PET) with [(18)F]FDG and [(18)F]NaF as well as X-ray computed tomography (CT), before being evaluated with the zirconium-89-labeled antibody specific for LTA ([(89)Zr]SAC55). Taken together, the radiolabeled anti-LTA mAb, [(89)Zr]SAC55, may serve as a valuable diagnostic molecular imaging probe to help distinguish between sterile inflammation and infection in the setting of PJI. In conclusion, we have demonstrated the ability of an anti-LTA mAb immunoPET imaging probe to discriminate infection from non-specific inflammation in a preclinical mouse model of PJI.	./cache/cord-002985-2rtk9ppu.txt	./txt/cord-002985-2rtk9ppu.txt