id author title date pages extension mime words sentences flesch summary cache txt cord-003070-6oca1mrm Shen, Wen-Jun RPiRLS: Quantitative Predictions of RNA Interacting with Any Protein of Known Sequence 2018-02-28 .txt text/plain 5476 339 56 On the non-redundant benchmark test sets extracted from the PRIDB, the RPiRLS method outperformed RPI-Pred and IPMiner in terms of accuracy, specificity and sensitivity. The computational results showed that the RPiRLS classifier outperformed the RPiRLS-7G classifier in terms of various performance measurements, indicating that the diversity of amino acids at a sequence is important for the prediction of RPIs. The performance of predicting RPIs was evaluated by using 10-fold stratified cross-validation on the RPI2662 data set. For the RPI369 data set as shown in Table 4 , the performance of the RPiRLS method was 0.85, 0.92, 0.84 and 0.86 for predictive accuracy, AUC, specificity and sensitivity, respectively. The work presented here provided a computational method, called RPiRLS, to classify RNA-protein pairs as interacting or non-interacting by integrating a sequence-based derived kernel with regularized least squares. ./cache/cord-003070-6oca1mrm.txt ./txt/cord-003070-6oca1mrm.txt