id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003131-o7j6xq4s	Tan, Shanfeng	CXCL9 promotes prostate cancer progression through inhibition of cytokines from T cells	2018-06-11		.txt	text/plain	3726	227	51	Results revealed that prostate cancer pathology and cell proliferation in CXCL9+DMAB mice were significantly greater compared with the C57+DMAB mice. In addition, reverse transcription-quantitative polymerase chain reaction analysis demonstrated that CXCL9 mRNA expression in clinical samples was positively associated with clinical pathological stages of prostate cancer. The results demonstrated that high expression of CXCL9 downregulated the levels of IL-6 and TGF-β in tumor tissues compared with C57+DMAB mice (Fig. 3A and B) . Therefore, it was concluded that CXCL9 reduced the secretion of IL-6 and TGF-β via the reduction of the number of T cells in immune organs and the tumor microenvironment, and promoted the development of prostate cancer. CXCL9 overexpression reduced the number of T cells in immune organs and the tumor microenvironment, and reduced the secretion of IL-6 and TGF-β2, and thereby promoted the development of prostate cancer.	./cache/cord-003131-o7j6xq4s.txt	./txt/cord-003131-o7j6xq4s.txt