id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003261-fz8ucwwm	Freundt, Eric C.	Innate Immune Detection of Cardioviruses and Viral Disruption of Interferon Signaling	2018-10-12		.txt	text/plain	7890	426	48	L * is only expressed by TMEV and is important for infection of macrophages, persistence of the virus in mice and inhibiting RNase L (van Eyll and Michiels, 2000; Sorgeloos et al., 2013) , 2B * results from a frameshifting mechanism conserved in cardioviruses that regulates the ratio of structural and non-structural proteins translated over time. (2012) , which was based on Influenza virus infection and suggests that PKR triggers the formation of "antiviral stress granules" that serve as a recruitment platform for dsRNA and RIG-like helicases, thereby enhancing IFN production. Like 3C proteases of other picornaviruses that were shown to target critical factors involved in IFN induction such as RIG-I (Barral et al., 2009) , EMCV 3C was reported to cleave TRAF family member-associated NF-kB activator (TANK) in infected cells, thus disrupting the complex involving TBK1, IKKe and IRF3 and limiting type I IFN production (Huang et al., 2017) .	./cache/cord-003261-fz8ucwwm.txt	./txt/cord-003261-fz8ucwwm.txt