id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003420-nnoni7qb	Huang, Wan-Ping	mRNA-Mediated Duplexes Play Dual Roles in the Regulation of Bidirectional Ribosomal Frameshifting	2018-12-04		.txt	text/plain	8931	387	50	The −1 PRF efficiencies induced by a downstream dnaX hairpin in the presence of upstream internal SD mediated duplexes with different spacings toward the frameshifting site ( Figure S1B ,D) were similar to those reported in vivo [12] , indicating that the experimental platform can faithfully reproduce this −1 PRF model system. To compare upstream hairpins with SD anti-SD duplexes in frameshifting regulation, we used the A6G slippery sequence with a modified pseudoknot (mPK) derived from the infectious bronchitis virus (IBV) 1a/1b gene [14, 23] , and the CUUUGA frameshifting site of RF2 for −1 and +1 PRF analysis, respectively ( Figure 1) . (D) Radioactivity-based +1 PRF assay by SDS-PAGE analysis of 35 S methionine-labeled in vitro translation products, with calculated +1 frameshifting efficiencies shown, for different upstream duplex constructs in (A).	./cache/cord-003420-nnoni7qb.txt	./txt/cord-003420-nnoni7qb.txt