id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003600-cpbbjm13	Georgakouli, Kalliopi	Exercise in Glucose-6-Phosphate Dehydrogenase Deficiency: Harmful or Harmless? A Narrative Review	2019-04-04		.txt	text/plain	3315	170	36	Glutathione (GSH), a significant antioxidant molecule, levels are lower in G6PD individuals, and theoretically, the probability of oxidative stress and haemolysis due to exercise in individuals with G6PD deficiency is increased, whereas dietary supplementation with antioxidants may have beneficial effects on various aspects of this enzymopathy. RESULTS: There is little evidence indicating that G6PD deficiency can cause perturbations in redox status, haemolysis, and clinical symptoms such as fatigability and myoglobinuria, especially after intense exercise, compared to individuals with normal enzyme levels. Finally, since GSH levels are lower in G6PD deficiency, it would be interesting to examine the effects of antioxidant or cysteine donor supplements on redox status after exercise in these individuals. As mentioned earlier, there are reports in the literature that come from case studies with no rigid research designs, which report that heavy exercise in G6PD-deficient individuals caused clinical signs of haemolysis, muscle degeneration, myalgia, and myoglobinuria, which may be attributed to increased oxidative stress [15, 16, [24] [25] [26] .	./cache/cord-003600-cpbbjm13.txt	./txt/cord-003600-cpbbjm13.txt