id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005589-ocnce92z	Torres, Antoni	Challenges in severe community-acquired pneumonia: a point-of-view review	2019-01-31		.txt	text/plain	6052	313	36	In this point-of-view review paper, a group of experts discuss the main controversies in SCAP: the role of severity scores to guide patient settings of care and empiric antibiotic therapy; the emergence of pathogens outside the core microorganisms of CAP; viral SCAP; the best empirical treatment; septic shock as the most lethal complication; and the need for new antibiotics. The IDSA/ATS criteria remain the most pragmatic and robust tools to predict patients requiring ICU admission We recommend empirically covering PES pathogens in SCAP when at least two specific risk factors are present Corticosteroids can be used in cases of refractory shock and high systemic inflammatory response Based on available data, new antibiotics providing existing limitations in empiric therapy (including macrolide resistant species and MRSA) are needed 38.6% previously) and reduced delayed ICU admissions. A recent observational study found that corticosteroid administration as adjuvant therapy to standard antiviral treatment in critically ill patients with severe influenza pneumonia was associated with increased ICU mortality [46] .	./cache/cord-005589-ocnce92z.txt	./txt/cord-005589-ocnce92z.txt