id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005808-w0763esk	Moreno, Gerard	Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study	2018-08-03		.txt	text/plain	5146	311	41	CONCLUSION: Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co-adjuvant therapy. Therefore, the aim of the present study was to identify the factors associated with corticosteroid use and its impact on intensive care unit (ICU) mortality using propensity score (PS) matching analysis in ICU patients with influenza pneumonia. Our results strongly suggest that administration of corticosteroids as co-adjuvant therapy to standard antiviral treatment in critically ill patients with severe influenza pneumonia is associated with increased ICU mortality. Three recent systematic reviews and meta-analyses [41] [42] [43] concluded that corticosteroid therapy is significantly associated with mortality, even in the subgroup of patients with influenza hospitalized in or outside the ICU. In a homogeneous group of critically ill patients with severe influenza pneumonia, after adequate adjustment by PS matching and competing risks, co-adjuvant corticosteroid therapy was significantly associated with increased ICU mortality.	./cache/cord-005808-w0763esk.txt	./txt/cord-005808-w0763esk.txt