id author title date pages extension mime words sentences flesch summary cache txt cord-009590-3w2weox4 Fredman, Gabriella The inflamed sputum in lower respiratory tract infection: l‐lactate levels are correlated to neutrophil accumulation 2019-01-06 .txt text/plain 3861 201 47 Because it is difficult to differentiate viral and bacterial infection on the basis of clinical presentation in LRTI, our secondary aim was to evaluate if l‐ and d‐lactate may serve as markers of local inflammation as representatives of neutrophils and bacteria, respectively. Increased markers of neutrophilic inflammation in sputum have been found to be associated with bacterial infection in COPD exacerbations (3), potentially leading to increased levels of both L-lactate and D-lactate. Increased markers of neutrophilic inflammation in sputum have been found to be associated with bacterial infection in COPD exacerbations (3), potentially leading to increased levels of both L-lactate and D-lactate. Altogether, we aimed to assess the utility of sputum L-lactate and sputum D-lactate as markers of pulmonary neutrophilic inflammation and bacterial invasion in the lungs of patients admitted with acute LRTI. Our study has shown that L-lactate in sputum is associated with the neutrophil invasion in the lungs Mixed bacterial/viral LRTI n = 2 (7.7%). ./cache/cord-009590-3w2weox4.txt ./txt/cord-009590-3w2weox4.txt