id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017148-o9qg2qta	Mocchegiani, Eugenio	Role of Zinc and Selenium in Oxidative Stress and Immunosenescence: Implications for Healthy Aging and Longevity	2019-04-11		.txt	text/plain	14893	679	40	These two trace elements display a common pivotal role in establishing the cellular antioxidant response as well as in mounting a proper immune response, which in turn may be useful to prevent excessive accumulation of senescent cells in aging and to reduce the senescence-associated increase of chronic inflammatory mediators. Old literature documented that zinc supplementation performed throughout the whole life span of rodents is able to delay some age-related cell-mediated immune modifications, such as the decreased circulating thymic hormone levels (Iwata et al. Dietary zinc and selenium are important nutritional factors for the immune response in protecting against the appearance of age-related diseases. These findings suggest that low dose supplementation of zinc and selenium provides significant improvement in elderly patients by increasing the humoral response after vaccination and decreased influenza compliances (respiratory tract infections) with thus a possible impact on the maintenance of health conditions during aging.	./cache/cord-017148-o9qg2qta.txt	./txt/cord-017148-o9qg2qta.txt