id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-032183-yqqqe325	Ning, Qin	Antiviral Therapy for AECHB and Severe Hepatitis B (Liver Failure)	2019-05-21		.txt	text/plain	32675	1658	43	Patients awaiting liver transplantation because of HBV-related end-stage liver disease or liver cancer should be given nucleoside analogues with strong HBV inhibition and low drug-resistance, or nucleotides analogues combination treatment, in order to reduce viral load and prevent graft re-infection. The objective of antiviral treatment for HBV-ACLF is to reduce viral load at an appreciably high rate, thereby promoting reduction in hepatocyte cell death and improved survival outcomes by prevention of decompensation related multiorgan complications in this group of severely ill patients. Response-Guided Therapy 4006 study [126] suggested continuous treatment with LAM (10 years) delayed clinical progression in patients with chronic hepatitis and advanced fibrosis by significantly reducing the incidence of the risk of hepatocellular carcinoma and hepatic decompensation.	./cache/cord-032183-yqqqe325.txt	./txt/cord-032183-yqqqe325.txt