id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252230-s1qd3x1b	Cadwell, Ken	Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins	2018-03-05		.txt	text/plain	6745	350	34	Thereafter, several groups identified autophagy-related proteins (ATGs), evolutionarily conserved molecules that control fundamental aspects of the macroautophagy pathway, including the formation of autophagosomes, double membrane vesicles that capture cellular cargo and subsequently deliver them to the lysosome for degradation (Tsukada and Ohsumi, 1993; Thumm et al., 1994; Harding et al., 1996) . Among these, macroautophagy (hereafter called autophagy) is the most well studied and genetically controlled by ATGs. Classic autophagy proceeds through multiple "canonical" steps that include (1) initiation by an autophagy-inducing signal, (2) nucleation of an isolation membrane or phagophore assembly site, (3) elongation and sealing of this double membrane around the cargo to be sequestered to form an autophagosome, (4) docking and fusion of the autophagosome with the lysosome to form an autolysosome, and (5) degradation of the vesicle contents by lysosomal enzymes ( Fig. 1 A) .	./cache/cord-252230-s1qd3x1b.txt	./txt/cord-252230-s1qd3x1b.txt