id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-263322-y4htkvux	Yang, Jun	Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis	2019-05-14		.txt	text/plain	4421	233	47	title: Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis The studies were included in our meta-analysis if they met the following criteria: (1) case-control or cohort studies comparing a population that suffered SONFH with a population that did not suffer after steroid treatment, (2) studies assessing the associations between genetic polymorphisms and SONFH, and (3) studies reporting the frequencies of specific alleles or the effect sizes of individual genotypes between cases and controls. First, the present study found that the ABCB1 rs1045642 mutation has a protective effect on SONFH, and the risk will be further reduced with increasing cumulative steroid dosage. Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population	./cache/cord-263322-y4htkvux.txt	./txt/cord-263322-y4htkvux.txt