id author title date pages extension mime words sentences flesch summary cache txt cord-267816-84z9fp2u Magdi, Mohamed Severe Immune Thrombocytopenia Complicated by Intracerebral Haemorrhage Associated with Coronavirus Infection: A Case Report and Literature Review 2019-07-12 .txt text/plain 1089 81 48 title: Severe Immune Thrombocytopenia Complicated by Intracerebral Haemorrhage Associated with Coronavirus Infection: A Case Report and Literature Review Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that causes isolated thrombocytopenia. We describe the case of a healthy man who presented with severe ITP complicated by intracranial haemorrhage following upper respiratory tract infection. LEARNING POINTS: Coronavirus can cause severe immune thrombocytopenic purpura (ITP). We present a case of severe thrombocytopenia complicated by intracranial haemorrhage following infection with a coronavirus, which has not previously been reported. Clinical presentation varies from the more common petechiae, purpura and mucous membrane bleeding (epistaxis or gum bleeding) to the rare severe gastrointestinal or intracranial bleeding, which has been reported in 1.4% of patients [3] . [8] described a patient with severe thrombocytopenia associated with varicella zoster infection whose platelet count returned to normal after antiviral treatment. Infection with coronavirus (CoV) has been associated with severe acute respiratory syndrome (SARS). In contrast, we report severe thrombocytopenia following mild coronavirus upper respiratory tract infection. ./cache/cord-267816-84z9fp2u.txt ./txt/cord-267816-84z9fp2u.txt