id author title date pages extension mime words sentences flesch summary cache txt cord-268142-lmkfxme5 Schafrum Macedo, Aline Animal modeling in bone research—Should we follow the White Rabbit? 2019-09-26 .txt text/plain 3706 296 49 title: Animal modeling in bone research—Should we follow the White Rabbit? Our aim here is to provide a broad overview of animal modeling and its ethical implications, followed by a narrower focus on bone research and the role rabbits are playing in the current scenario. 12 Five key bioethical points are considered when assessing the moral status of animal subjects in research: the presence of life, the ability to feel and perceive stimuli, the level of cognitive behavior, the degree of sociability, and the ability to proliferate. Animal models have taught us much about bone disorders and have been central to developing many treatments throughout history. 8, 17, 51 Rabbits are appealing models for bone research. Rabbits have potential as bone models but conclusive studies are still lacking. Animal models for implant biomaterial research in bone: a review The laboratory rabbit: an animal model of atherosclerosis research Osteoporosis-bone remodeling and animal models ./cache/cord-268142-lmkfxme5.txt ./txt/cord-268142-lmkfxme5.txt